21 8 
Chapter XXII 
Clinical Study of Malaria 
The Leucocytes in Malaria 
We shall consider (i) the total leucocytes, (2) the 
percentage value of each kind. 
The Total Leucocytes .—We may take 10,000 as 
the normal value per mm. 3 , and as 5,000,000 is the 
normal value for red cells, the proportion of white to 
red is 
WC _ 10,000 _ 1 
RC 5,000,000 500 
Now, in malaria, we may find two conditions, 
either that the total number of leucocytes is con¬ 
siderably below the normal value, 10,000, i.e ., there 
is leucopenia or hypoleucocytosis, or that the total 
number is much above 10,000, i.e., leucocytosis. If 
there is leucopenia, say, for instance, the total number 
is 5,000 instead of 10,000, then 
WC 5,000 1 
RC 5,000,000 1,000 
is smaller than normal. 
i.e.. the fraction 
WC 
RC 
If, on the contrary, the total leucocytes are 
20,000 instead of 10,000, i.e., leucocytosis, then 
WC 
RC 
20,000 
5,000,000 
-, i.e.. the fraction 
250 
WC 
RC 
is greater than normal. 
