34 8 
(2) Period of ‘ Plaques ’ :—In forty to fifty days 
after coitus well defined areas as big as a shilling or 
crown piece appear, representing angioneurotic 
oedematous patches. These plaques last a week or so, 
or map suddenly appear and again disappear. 
(3) Periods of paralysis and extreme anaemia :— 
Skin abscesses and eye symptoms occur. Paralysis of 
the hind quarters develops, so that the animal cannot 
stand. Death occurs in two to ten months or even 
much later. Ruminants are refractory to inoculation. 
Blood Examination. —Trypanosomes are found 
only with great difficulty, but fairly easily in the area 
of a plaque if examined at its first appearance. 
Morphology. —25-28/* long. The protoplasm does 
not as in T. brucei contain chromatin granules, and the 
posterior end is often slightly cleft. 
Transmission. —Is effected by coitus of an infected 
stallion with a mare or vice versa. The resemblance 
to syphilis should be borne in mind. 
Pathology. —The inguinal lymphatics and testes 
are infiltrated and caseous. According to Mott, follow¬ 
ing the primary sore there is inguinal gland enlargement, 
then general gland enlargement. The virus is con¬ 
veyed along the lymphatics of the pelvic plexus of 
nerves to the lumbo-sacral ganglia primarily, and to all 
the spinal ganglia eventually. This leads to the angio¬ 
neurotic eruption (plaques) which may subside leaving 
no trace, or it may end in patches of leukoplakia if the 
inflammation be intense enough to destroy the 
ganglion cells. Likewise secondary degeneration of 
the posterior roots, causing an ataxic condition of the 
hind legs, or a general neuritis may be associated and 
cause paraplegia. 
6. T. theileri. —The cause of a disease in South 
Africa known as gal-ziekte (gall sickness). A similar 
