370 
Leucocytic Changes 
Leucopenia is the most marked change. So much 
is this so, that it is necessary to take several large films 
in order to make accurate leucocytic counts. Two 
thousand leucocytes per mm. 3 is a common value and 
still smaller numbers are not uncommon. The relative 
leucocytic values, however, do not vary much from the 
normal, and are quite unlike those of malaria. 
Case I 
| 
Case II 
CaseUI 
Case IV 
Large mononuclear 
- 
- 
ir 4 
8-6 
io’6 
i6‘o 
Transitional 
- 
- 
i’8 
o - 6 
— 
— 
Small mononuclear 
- 
- 
2\'6 
2oq 
29’2 
7'° 
Myelocytes 
- 
- 
I '2 
0'2 
o '6 
— 
Polynuclear 
- 
- 
6o*o 
6 q '8 
56’ 0 
73'° 
Eosinophil - 
- 
- 
ro 
°'4 
3'6 
4'° 
Post-Mortem Changes 
Spleen .—The appearance of the spleen and the 
liver are almost pathognomonic. The spleen retains 
its shape when removed from the body as if hardened 
in situ. It is firm but friable, not tough like a fibroid 
spleen. 
Liver .—Firm but friable, retaining its shape like 
the spleen on removal. On cutting into it an arbores¬ 
cent appearance is noticed, due to the deposit of a white 
tissue (macrophages containing parasites) in the centre 
of the lobules. 
