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colour of the face, the flushing of one or both cheeks, the clear eyes, 
with the irritated state of the pulse, are sufficient to point out the dis¬ 
ease and distinguish it from typhus. 
When in combination with typhus, all the symptoms are aggra¬ 
vated in severity after the fourteenth day, and then become more 
distinctly marked. This disease is an equally frequent accompani¬ 
ment of smallpox as of typhus, and presents the same morbid ap¬ 
pearances on post-mortem inspection. 
In those who have died of this disease, of the mucous membrane, 
of the intestines, the blood in the heart and large vessels presents 
the same appearances as in those who have died of chronic inflam¬ 
matory disease, in this respect differing from its appearance in typhus 
cases. 
The observations on which these facts are founded were not made 
to establish any theory. The reports of the cases and post-mortem 
inspections are made in the presence of all who choose to witness 
them; the facts only are pointed out, and all are at liberty to draw 
their own conclusions from them. 
These sixteen propositions, the result of careful observation in up¬ 
wards of three thousand cases and two hundred post-mortem inspec¬ 
tions, are considered as facts fully ascertained. The following are 
believed, but sufficient evidence cannot as yet be adduced to prove 
them. 
1st. That typhus fever does not become infectious till the sixth 
day, and is most contagious when the patient is in the convalescent 
state, when cuticular desquamation usually occurs : 
2nd. That the contagious poison is chiefly spread by the disqua- 
mation of the cuticle during the period of his convalescence : 
3rd. That the earliest period of the disease making its appearance 
after exposure to contagion is eight days, more frequently fourteen, 
and sometimes as long as two months: 
4th. That in every case of genuine typhus fever the vessels rami¬ 
fied upon the pia mater are more or less enlarged or congested, and 
throw out a serous fluid betwixt the convolutions of the brain and 
on its surface, which to a certain degree compresses this organ and 
impairs its functions, and along with the morbid state of the blood 
is frequently the cause of death in this disease. 
On the Use of Chloride of Soda in Fever, By Rob. J. Graves, M.D. 
Dr. Graves commenced a series of clinical experiments in 1832 
upon the efficacy of chloride of soda in petechial and maculated 
fever. He has exhibited this medium at Sir Patrick Duns Hospital 
and at the Meath Hospital, where its effects have been witnessed by 
a great number of physicians as well as pupils. The form recom¬ 
mended is Labarraque’s solution, which is a saturated solution of 
chloride of soda. This was given in doses of from fifteen to twenty 
drops in an ounce of camphor mixture every fourth hour. In the 
