C. H. Treadgold 129 
were Loas; three of them were found in the subcutaneous tissues, while the 
remaining three came from the pericardium, the peritoneal cavity and the 
upper surface of the diaphragm respectively; the seventh was found between 
the layers of the mesentery and did not belong to the genus Loa. 
The distribution of Microloa papionis. When larvae were discovered in the 
peripheral circulation of the host during life, they were invariably present at 
night 1 ; they were less numerous or absent in the daytime. (Table VI.) 
In five animals in which the peripheral blood had been examined with 
negative results during life, larvae were found in the heart’s blood at the 
autopsy. (Table VI.) 
In another case, no larvae were found either during life or at the autopsy: 
nevertheless Dr Query exposed an adult Loa under the skin of the neck when 
bleeding the animal, while two more were found at the autopsy after a pro¬ 
longed search. No larvae were discovered in citrated and centrifuged blood 
from the heart and carotid artery, and smears made from the lungs and 
other organs were also negative. The worms proved on examination to be 
full grown but unimpregnated females. These facts are interesting in that 
they possibly explain a point raised by Low (1913) as to the “occasional 
absence of larvae from human blood in cases where adult females are known 
to be present in the tissues.” ' 
Table VI. 
The periodicity of Microloa papionis. 
% 
Percentage of 
Peripheral blood during life 
« 
Day 
Night 
Carotid 
(at operation) 
Heart’s blood 
(at autopsy) 
No. 14 
o* 
_ * 
+ 
+ 
No. 17 
o 
+ 
+ 
+ 
No. 18 
o 
+ 
o 
o 
No. 24 
+ scanty 
+ 
+ 
+ 
No. 28 
O 
O 
1 
T 
+ 
No. 31 
O 
— 
+ 
+ 
No. 36 
— 
o 
+ 
— 
No. 38 
+ 
+ 
+ 
+ 
No. 39 
O 
+ 
+ 
+ 
No. 42 
o 
— 
+ 
+ 
No. 48 
+ scanty 
4- 
+ 
— 
No. 55 
4- scanty 
+ 
— 
— 
positive results 
36-3 
77-7 
909 
88-8 
* + signs denote that Microloa were found, O signs denote negative results, and - signs 
indicate that no examination was made. 
At the autopsy, the larvae were chiefly concentrated in the heart, lungs 
and large pulmonary vessels: it is possible, however, that the preliminary 
bleeding of the host affected their distribution to some extent. In the two 
animals in which a careful search was made, the distribution of the larvae was 
1 The animals were usually examined between midnight and l a.m. 
9-2 
