376 
Leishmania, Herpetomonas, and Crithidia 
this disease. I think that in the Mediterranean regions leishmaniasis may be 
much more frequent than has yet been ascertained, and that slight cases, not 
easily to be diagnosed, may be particularly frequent. 
The facts obtained by my long-continued researches into visceral leish¬ 
maniasis in the Mediterranean regions, the epidemiological factors of the close 
relations between leishmaniasis in children and in dogs, the close relations of 
contact between children and dogs affected with leishmaniasis and fleas in¬ 
fected with parasitic protozoa which are morphologically and biologically 
indistinguishable from Leishmania, afford ever-increasing confirmation of the 
results of my investigations, and tend to prove that the visceral leishmaniasis 
of the Mediterranean is produced by a species of Herpetomonas of Pulex 
irritans and Ctenocephalus canis which has adapted itself to live in children 
and dogs, themselves the habitual hosts of these fleas. 
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