46 
Trypanosomiasis of Camels 
was reduced to 3 days (5-7 days in the absence of parasites in the blood) 
after intraperitoneal inoculation, and 4 days after subcutaneous inoculation; 
death occurred in 8-10 days after infection. 
No symptoms of the disease were observed during life. 
Grey rats are also easily infected. The incubation period, after inoculation 
with virus invigorated through passage in mice, is 4 days. The number of 
trypanosomes increased every day. Death took place on the 9th day after 
infection and 5 days after the appearance of the parasites in the blood. 
(c) Rabbits. For these animals the trypanosomes appear in the blood 
after the following periods: 
4-13 days after intravenous inoculation. 
4-7 ,, ,, intraperitoneal ,, 
10-13 ,, ,, subcutaneous ,, 
Death occurred: 
on the 46th dav after intravenous inoculation. 
«/ 
,, 13th ,, „ intraperitoneal ,, 
,, 71-80 ,, ,, subcutaneous ,, 
After the appearance of trypanosomes in the blood: 
on the 35th day after intravenous inoculation. 
,, 30-70 ,, ,, subcutaneous ,, 
r 
On two rabbits we observed the temperature curve: 
Rabbit No. 1. Inoculated subcutaneously on March 12th, T. 39-0° C. 
On the 13, 14, 15, 16, 17 and 18th the temperature rose progressively to 39-8°. On the 
19th it was 39-1 °, later again a rise to 39-8° (21st). On the 22nd till April 26th trypanosomes 
appeared in the blood, T. 39-6°. Later the temperature was between 39-8° and 40-5°. On 
the 27th and 28th April the temperature was 39-6° and on the 29th the rabbit succumbed. 
Rabbit No. 2. Inoculated into the vein on the 12th March; T. 38-8° C. On the following 
days the temperature fluctuated between 38-7° and upward. On the 20th, when trypano¬ 
somes appeared in the blood, the temperature rose to 40-1°. 
Until the first days of April the curve fluctuated in the limits between 39-5° and 40-6°; 
after that period it ranged between 38-8° and 40-6°. 
The day before death it was 39*2°. 
In rabbit No. 4 the temperature once reached 41*2°. 
In nearly all our rabbits we succeeded in establishing the presence of trypanosomes in 
the blood. The quantity of them was never great—from + v.f. to + and only in one case 
+ + + +. The parasites rarely appear in the blood. 
During the disease the rabbits emaciate considerably. No oedema is 
observed. The blood becomes pale. 
( d) Guinea-pigs. It is in these animals that our virus from Turkestan 
camels was chiefly maintained. 
The period of incubation depends on the quantity of trypanosomes 
introduced, and as in mice there is always a larger number of parasites than 
in other animals, the guinea-pigs inoculated from mice are infected earliest. 
