48 
Trypanosomiasis of Camels 
between 38-9°-408°. Finally the animal succumbed. After intraperitoneal 
inoculation the trypanosomes appear in the blood after 4 days, and after 
subcutaneous treatment, according to the amount of virus introduced, after 
5-8 days. 
The quantity of trypanosomes varied from 4- v.f. to + + + . 
The parasites are nearly always present in the blood. 
In dog No. 1 the trypanosomes appeared on the 5th day but disappeared 
during the succeeding 2 days. 
On the 8th day they were visible in the blood, disappearing on the 9th, 
but from the 10th to the 14th they were present. 
On the 15th day they were absent, but were present from the 16th to the 
22nd. 
On the 23rd day they were absent. 
From the 24th till the 26th they were present, but on the 26th and 27th 
they were absent. 
Thence they were present from the 30th till the day of death (35th), 
increasing in numbers all the time. 
As we have seen, from the time of the appearance of trypanosomes in 
the blood up to the day of death there were five brief periods (1-2 days) 
during which no trypanosomes were present in the blood. They were, however, 
indubitably present, but were so scarce, that it was impossible to detect 
them with the microscope. 
Thus, the appearance of trypanosomes in the blood and their numbers 
correspond with the rises of temperature. There is no doubt that the 
temperature is due to the toxin produced by the trypanosomes. 
In the days of high temperature the animals are dull, feed badly and are 
indifferent to their surroundings. 
During the disease they emaciate considerably, so that sometimes they 
present the aspect of a skeleton covered with skin. Dog No. 1 was reduced 
in weight during 35 days of disease from 22 lbs. to 15J lbs. 
Oedemas are always present, chiefly on the abdomen and also on the 
head (oedema of the eyelids). Keratitis is often observed. Sometimes pareses 
and diarrhoea occur. Death occurs in complete apathy. The blood becomes 
pale (oligocythaemia, oligochromaemia). (For a special investigation of the 
blood of dog see below, p. 63.) 
(/) Sheep. Sheep are also susceptible to infection with this camel try¬ 
panosome. 
One ram was infected subcutaneously on the 12th March, 1917. 
The trypanosomes first appeared in small numbers after 21 days, then 
disappeared and never re-appeared in the blood. 
The temperature rose from the initial 39-5° to 40*3° in 6 days after infection, 
then fluctuated between 39*2° and 40-8°, but was more regular in the 4th 
month (fluctuations between 38-9°-40-3°). 
