W. L. Yakimoff and others 
53 
On the 51st day they numbered 3,680,000 per cub. mm. 
,, 65th ,, ,, 3,456,000 ,, 
,, 72nd ,, ,, 3,368,000 ,, 
„ 79th „ „ 2,608,000 
Thus the erythrocytes have decreased to 28-85 % of their original number. 
Besides the quantitative change, there is also a change in quality. 
Beginning from the 10th day after infection, agglutination of the red 
blood corpuscles is observed, from the 13th— normoblasts, and from the 17th 
— polychromatophilia. 
(2) Haemoglobin. The percentage of haemoglobin was estimated daily. 
Prior to infection it amounted to 80 % and already on the 5th day of the 
disease it had dropped to 70%. Later the percentage diminished more 
gradually. 
From the 5th till the 6th day after infection—70 % 
7th 
55 
8th 
55 
„ -65 
10th 
55 
16th 
55 
„ -60 
17 th 
55 
22nd 
55 
„ —55 
23rd 
55 
45th 
55 
„ -50 
47th 
>> 
day of death 
—45 
thus 43-7 % of the amount of haemoglobin was lost. 
Colour index. Assuming the number of red blood corpuscles in this 
animal to be equal to 1, and the amount of haemoglobin also equal to 1, the 
colour index would be equal to 1. 
After infection, during the first half of the disease, the index was less 
than 1: 
On the 8th day—0-7 
„ 13th „ —0-9 
,, 18th ,, —0-8 
But from the 36th day it began to increase; on this day it was equal to 1-1. 
After 36 
day 
r s it was 
M 
„ 73 
55 
55 
1-5 
„ 57 
55 
55 
1-5 
„ 72 
55 
55 
1-5 
„ 79 
55 
(3 days before 
death) 1-8 
Such a difference is due to the fact that during the first half of the infection 
the diminution of the haemoglobin percentage proceeded more rapidly than 
the decrease in red blood corpuscles; whereas, during the second half, the 
relations were reversed: the red blood corpuscles were being destroyed more 
rapidly than the remaining elements dehaemoglobinized. 
