54 
Trypanosomiasis of Camels 
(3) White blood corpuscles. The most interesting phenomena observed 
relate to the leucocytes. On the day after infection their number rose from 
an average of 10,207 per cub. mm. to 17,105, and remained at this height three 
days longer. On the sixth day the curve descended to the normal and up to 
the 15th day it remained on this level, or even lower (to 5,725). 
From the 15th day (4 days before the appearance of trypanosomes in the 
blood) the curve began to rise, until on the 17th day (one or two days before 
the appearance of trypanosomes) it reached the number of 17,853. 
Later there came again a period of decrease, until the 27th day, when a 
new rise occurred, and a day before the second appearance of trypanosomes 
in the blood (which took place on the 30th day) the curve rose to 18,480. 
In this second period of the appearance of trypanosomes in the blood the 
curve, which had fallen on the first day of this period to the normal, again 
began to ascend, and on the day following the disappearance of the trypano¬ 
somes it reached the highest point during the whole course of the disease 
(24,641). 
After this the curve began to descend during the 4 succeeding days, to 
rise again on the first day of the third period of appearance of trypanosomes 
in the blood (41st day) to 20,720, and further—even to 22,659 (43rd day). 
In the interval between the 47th and 57th days, when no trypanosomes 
were present in the blood, the number of leucocytes fluctuated between 
12,269 and 17,563, but after the last date (49th day) tended to diminish. 
With the next—fourth—appearance of trypanosomes in the blood (57th 
day) an increase in the number of leucocytes was again observed (57th day, 
14,560, 58th, 15,222 and 59th, 15,529). 
Further there were several more rises of the curve of leucocytes, sometimes 
accompanied by the presence of trypanosomes in the blood, and sometimes 
not. 
From the above it may be assumed that during trypanosomic infection 
in the foal there occur four periods of leucocytosis: 
(1) Initial, short, during 4 days (2-5 days), due to the spread of the 
infection in the organism. 
(2) Also short, coinciding with the appearance of trypanosomes in the 
blood. 
(3) The longest, during 39 days (from 28th till 66th day). This whole 
period may be called the period of leucocytosis, notwithstanding that the 
curve descended twice to the normal, and even lower. 
(4) A shorter period of leucocytosis during 12 days (from the 70th till 
the day of death), in the course of which there were two falls, and the curve 
in general was not so high as in the third period. 
The proportion of leucocytes to red blood corpuscles before infection was 
1:840. Later, in the first period of the disease it increased (1:1240—on 
the 13th day), but as the infection advanced the ratio was less than the 
initial: 
