58 
Trypanosomiasis of Camels 
fection. From the primary average of 5-5 % the curve began to rise, and on 
the 21st day reached the maximum 36-3 %. Later the curve varied, but did 
not descend below 8-2 %, and only once rose to 25*3 %. The curve of leuco- 
cytosis was in inverse relation to the curve of the total number of leucocytes. 
(6) The alkalinity of blood. Estimated by Engel’s method, the alkalinity 
decreased visibly as the disease progressed, as seen 
in the following table: 
Prior to infection ... 
0-58455 
On the 13th day after infection 
0-56290 
,, 25th ,, 
0-38970 
„ 35th 
0-34640 
,, 51st ,, ,. 
0-32475 
„ 57th 
0-34640 
„ 66th 
0-34640 
„ 75th 
4 
0-25980 
Thus, we observe in horses the same phenomenon, that had been witnessed 
by Yakimofl in dogs infected by trypanosomes, i.e. a decrease in the alkalinity 
of blood (53-8 %). However, Nierenstein, who revised Yakimoff 5 s experi¬ 
ments, regards this phenomenon not as a decrease in alkalinity, but as an 
increase in the acidity of blood. 
On considering this disease in the horse from the haematological point of 
view, we see that the blood picture is due chiefly to the following: 
(1) olygocythaemia, 
(2) oligochromaemia, 
(3) leucocytosis, 
(4) lymphocytosis, 
(5) shift of the Arneth index to the left, and 
(6) decrease in the alkalinity of blood. 
The general 'picture of the life of the blood elements during trypanosomic 
infection in the horse may be represented as follows: 
First period. From the day of infection till the appearance of trypanosomes 
in the blood. 
Characteristic. Two primary leucocytoses. Beginning of leucocytolysis. 
Polynucleosis. Decrease in percentage of lymphocytes. Beginning of the 
“shift to the left” in the Arneth index. Beginning of decrease in the number 
of red blood corpuscles and the percentage of haemoglobin, and in the 
alkalinity. Decrease in the colour index. Widening of the correlation between 
the white and red blood corpuscles. 
This period may be called the period of the first lesser leucocytosis and 
polynucleosis. 
Second period. From the appearance of trypanosomes in the blood until the 
third period. 
