76 
Trypanosomiasis of Camels 
It is clear that, in this infection, trypan-blue is unsuitable as a trypanocide. 
Experiments with trypanil. In our experiments this compound was 
always administered intravenously and its toxicity is shown in Table 19. 
Table 19. 
Solution 
Results 
1:200 
Succumbed 
o 
o 
CO 
r—4 
o 
o 
r-i 
Recovered 
l : 500 J. 
Thus the dosis tolerata is the same as in the case of trypan-blue, 1 : 200. 
The trypanocidal action is shown in Table 20. In addition the preparation 
was injected subcutaneously and the mouse relapsed after 13 days (Table 21). 
Table 20. 
Days 
Solution 
1 
2 
3 
4 
5 
6 
7 
8 
9 
10 li 
1 • 200 
+ v.f.® 
0 
0 
0 
0 
0 
0 
0 
0 
recurrence 
1: 300 
+ v.f.@ 
+ f. 
+ 
+ + + 
+ + + 
+ + 
+ + 
+ + 
death 
l: 400 
+ V.f.® 
+ v.f. 
+ 
— 
+ + + 
+ + 
+ + 
+ + 
+ + 
+ + 
l: soo 
+ v.f.® 
+ 
+ + 
+ + + 
death 
+ + 
+ + 
+ + 
+ + + 
+ + death 
Table 21. 
Days 
Solution 
r 
1 
2 
3—12 
N 
13 
l: 
100 
+ v.f.® 
+ V.f. 
0 
recurrence 
Experiments with trixidin. This preparation consists of a 30 % oil emul¬ 
sion of antimony trioxide. For the estimation of its toxicity we have injected 
subcutaneously from 0-1 to 0-3 grammes of trixidin per 20 grammes of live 
weight. 
The results were as follows (Table 22): 
Dose of 
in grammes 
Table 22. 
Results 
Recovered 
Succumbed on 7th day 
Mice infected with this trypanosome were injected with various doses of 
this compound (subcutaneously in Province oil) from 0-0005 to 0-1 grammes 
per 20 grammes of weight of the mouse, which corresponds to a solution of 
the preparation from 1 : 2000 to 1 : 100. 
The results obtained were as follows (Table 23): 
