102 INQUIRY INTO A DISEASE OF THE HORSE 
or irregular, and short of duration, or any swelling of the sub¬ 
cutaneous lymphatic glands, or any bloody or ccdematous tumours 
upon the external surface; by the absence of all which it becomes 
distinguishable from malignant typhus ( charbonneuse ) fever, 
with or without superficial eruption. At this period, setons, 
sinapisms, vesicatories, &c. produce great swelling, with heat 
and tenderness, which speedily run into septic gangrene. 
The Blood shews remarkable alteration. It is deep black, and 
trickles down the skin from the vein. In the vessel it looks like 
an infusion of coffee. Coagulation takes place in ten or twelve 
minutes at most (which is less by six or eight minutes than in 
health), the buffed part of the clot exhibits a deep yellow or 
saffron colour, and from twelve to twenty-four hours remains in 
the state of trembling jelly. Afterwards the clot acquires 
firmness ; though but a very sparing quantity of citron-coloured 
serum exudes from it. 
The duration of this second stage varies from two to five 
days. 
The third stage exhibits an augmentation in the severity of 
the symptoms. The weakness increases; loss of flesh is appa¬ 
rent ; the respiration grows deeper and more laborious; the 
pulse smaller and less perceptible ; the eyes sunken; the con¬ 
junctives dark red, often livid ; mouth more fetid ; swelled more 
in sheath ; flanks tucked up ; sometimes painful cramps in the 
hind limbs; sinking down,and with struggles expiring. 
Recovery seldom happens after the first stage has passed, 
without efficient remedy. 
The passing of the disease into the chronic stage is denoted 
by its continuance, by the supervention of debility in spite of 
remedy, and by relapses during convalescence. Its pathology 
seems to consist in intestinal inflammation complicated with the 
serious evil of some special alteration of blood. 
Post-mortem. — Carcass prone to ready decomposition. 
Muscles in places exhibiting yellow infiltration. A quantity 
of reddish serum in the abdomen. Intestinal (small) mucous 
membrane reddened and thickened, and in parts softened. 
The glands of Pryer and Brunner the same. Caecum and 
colon containing dried aliment, and bearing evident traces of 
acute inflammation. Liver yellow, and readily lacerated. The 
respiratory organs, air-passages, and nasal cavities normal. 
Cavities of the heart full of black blood imperfectly congealed. 
Sero-albuminous effusion into the pericardium. 
Resume. —So that the marks of intestinal inflammation ; the 
alteration of the liver; and the black colour and incomplete co¬ 
agulation of the blood ; are the chief lesions determinable in the 
