REVIEW. 
624 
some days may have manifested what is usually considered 
to be influenza, or epidemic catarrh, the symptoms of which 
will, for the most part, consist of sore throat of an obstinate 
nature, with fever more or less severe, with cough, loss of 
appetite, discharge of purulent matter from the nostrils, and 
general debility; when suddenly the whole changes, the 
limbs begin to swell, which swelling presents either an even 
surface (occupying the whole of the limbs), or it appears in 
lumps, or in masses, which are both large and numerous, 
also hot, hard, and painful, while those portions of the skin 
free from such swelling presents the blotchy elevations so 
common to the simple form of scarlatina. The membrane 
of the nose becomes also covered with large sized spots of an 
intense scarlet colour, while from the nostrils is discharged 
a mixture of blood, purulent matter, and serum. At this 
stage the soreness of the throat becomes excessive, accom¬ 
panied, of course, with a corresponding degree of difficulty 
in swallowing; the cough also becomes worse, and of a 
suffocative character. The pulse increases in number, 
reaching at times 90, or even 100 beats per minute, and is 
always of a weak or feeble character. The swollen limbs are 
excessively tender, and if the patient be left alone he will 
stand for hours nailed, as it were, to one place, and in one 
position ; it is only, indeed, with the greatest difficulty that 
he can be made to move at all. As the disease proceeds, or 
assumes more intensity, large blisters, or vesicles, appear 
upon the limbs, particularly around the joints ; these vesicles 
burst and discharge a bright amber coloured fluid, which is 
very corrosive in its effects upon the adjoining skin. In 
other cases again, some extreme portion of the organism, such 
as the ears, for example, will suddenly present a blanched 
appearance, the skin of these organs will shrink, and become 
hard and dry as though frozen, and in the course of a day or 
two these blanched portions snap off, leaving exposed a raw 
surface, which speedily suppurates. The appetite entirely 
disappears, and the secretions from the bowels, as a matter 
of course, become checked, and what is denominated consti¬ 
pation ensues; the urine also becomes scanty, and is of a 
thick yellow or of a brown colour. In the course of twenty 
or twenty-four hours from the commencement (and in many 
cases even less), the scarlet spots on the membrane of the 
nose enlarge and pass into purple-coloured patches, and 
these purple patches slough and leave a raw surface, from 
which is secreted an abundance of purulent matter: at the 
same time a similar sloughing goes on around the joints 
where the blisters, or vesicles, first appeared. If the animal 
