64 TUMOUR IN THE VENTRICLE OF THE BRAIN. 
some cases I have noticed numerous little bodies, like rows 
of flattened pearls, studding the free borders of the choroid 
plexus of the lateral and fourth ventricles; and in such 
instances I should imagine that cholesterine very much 
preponderated. As far as could be observed, the inner sur¬ 
face of the ventricles of the brain in question was much 
altered in form, doubtlessly by the pressure of the tumours. 
The body of the fornix was raised, and its posterior crura 
seemed to be much thinner than natural, and the foramen 
of Munro was also enlarged. The anterior portions of the 
thalami optici , especially their tubercles, were flattened. The 
gray commissure looked pale and disintegrated, as if it had 
been saturated with fluid; the septum lucidum was very thin; 
the corpora striata were very pale, flabby, and shrunken ; and 
the inner part of the anterior lobes of both hemispheres of 
the cerebrum was of a yellow tinge, and much softened. 
Such, as far as I could discover, were the chief lesions; 
others may have existed, but if so, the state of the organ 
precluded their being detected. 
We shall refrain from attempting to account for such 
phenomena as we suppose might have existed during the 
life of the animal, and which would correspond with the 
structural disease we have described, any further than simply 
to notice the inability of the horse to masticate; the time 
he would remain in a recumbent position apparently paralysed; 
and the coma which doubtless more or less existed. His 
inability to masticate was most likely caused by an inter¬ 
ference with the inferior division of the fifth nerve. The 
want of power, at times, to support himself, depended upon 
pressure on the region of the cerebellum, pons varolii, 
and medulla oblongata in particular; but was further 
influenced by the disease of the cerebrum. The coma 
depended upon pressure upon the inner substance, im¬ 
parted to it by the tumours and the fluid found in the 
ventricles, thus producing partial paralysis of the brain . 
An interesting account of similar concretions may be 
found by referring to the ‘Abstract of the Proceedings of the 
Veterinary Medical Association,’ 1837-8, p. 211. 
We have regretted the absence of a fuller account of the 
symptoms, which we believe must have existed in the above 
case, but which, during the life of the animal, were not 
observed as indicating cerebral disturbance. We neverthe¬ 
less cannot but feel indebted to Mr. Pyatt for giving us an 
opportunity of examining post-mortem the brain of an animal 
so singularly affected, as he has described this one to be, prior 
to his determining upon having the horse destroyed. 
