DISEASED SPLEEN. 9' 
the case, as they yielded comparatively little to the pressure 
of the fingers. 
On sections being made through the spleen, the cut sur¬ 
faces presented a similar varied aspect to that of its outer 
surface. No part of it, as far as could be detected, was 
normal. In some places it was quite black, in others nearly 
white; again, other parts varied in colour from an iron-gray 
to that of a brownish-gray. The two former, the black and 
white, greatly preponderated, and were so singularly inter¬ 
mixed as to give the parts the appearance of white and 
black marble. Further examination of these sections, even 
with the unaided eye, partly determined the character of this 
abnormal production. 
The black parts imparted to the finger or a piece of white 
paper a stain as if made with Indian ink. On testing the 
white parts in the same way, the finger or paper became 
simply moistened, having no greasy feel, nor did the paper 
appear as if grease had been applied to it. The precise 
nature of the former material seems easy to determine; it 
consisted of that which is very common in the spleens of 
old gray horses, namely, a deposit of pigment. But with 
reference to the latter, not being able to speak so confidently, 
a small portion of each was placed under the microscope, 
which revealed elements identical in character with those 
taken from a melanoid cancer, as figured in ‘ Paget^s Patho¬ 
logical Anatomy,^ p. 483, vol. ii, to which excellent work 
the reader is referred for an article on this disease. The 
matter scraped from the w'hite part of the cut surface had a 
peculiar creamy appearance, or it more nearly resembled 
that wdiich might be scraped from the cut surface of the 
brain. The dark and white parts being treated in the same 
way, yielded a dark, dirty, creamy mass. This material, 
when placed under the microscope, showed numerous pig¬ 
ment-granules, some free and others located in cells. Some 
of the corpuscles were large, and contained nuclei^ around 
w’hich the minute granules had clustered. Other cells, also 
of large size, but not so regular in form, contained nuclei 
and very firm granular matter in their interior. Besides 
these there were a few nucleated, oblong-shaped cells, which 
varied much in size. 
