CARCINOMA OF THE INTESTINES OF A HORSE. 131 
into the tube. Many of these abnormal growths had ulcerated 
through the mucous membrane, and discharged from their 
surfaces a bloody ichorous fluid, which I think must have 
discoloured the faecal matter, and I am surprised that this 
was not observed during the life of the animal. From the 
way the tumours had become united to each other, it was 
impossible to determine whether they involved more especially 
the glandular patches of Peyer or not, but I am inclined to 
think that these organs were primarily the seat of the 
disease. 
The siihstance of the coats of the intestines was next examined. 
—I have already stated that some of these tumours were 
subperitoneal, and others were beneath the mucous mem¬ 
brane. Occasionally, I found that those, in both situations, 
had completely collapsed; and that the muscular or middle 
coat was in consequence entirely displaced. In other places 
this tissue was only partially removed by the abnormal 
growth, and here and there the middle coat w^as considerably 
thickened by interstitial deposits of a semi-gelatinous con¬ 
sistence. 
The portion of the colon which I next examined w^as, wdth 
a slight variation in the situation and size of the tumours, 
similarly affected to the ilium. The enlarged mesenteric lym¬ 
phatic glands were softened, and some few of them had 
ulcerated through the thin peritoneal covering. On making 
a section through them, a brain-like substance was found in 
their interior, which to the unaided eye was dissimilar to 
that forming the substance of the tumours connected with 
the intestine. Microscopicall}'^, however, but little difference 
w^as observable in the elements of which they were composed. 
A portion of either, examined wdth one quarter inch power, 
brought to view a quantity of nucleated cells of various sizes. 
The larger ones, which varied very much in outline, con¬ 
tained a brood of younger cells. Some of these had burst, 
and yielded up their contents; but I could not discover any 
fusiform cells. These cells W'ere disseminated in a granular 
fluid, which was more abundant in the small quantity of 
material taken from the mesenteric glands than in that taken 
from the tumours in connection with the intestines. 
The head of the pancreas and the biliary duct, as it emerges 
from the transverse fissure of the liver, were also both 
affected with this cancerous development; and I have no 
doubt but that other organs w^ere similarly diseased. 
It is surprising to me that the horse retained his condition 
in the way I w^as informed he had; and this even up to the 
time he was destroyed. I should have expected, that if the 
