TRANSLATIONS FROM CONTINENTAL JOURNALS. 501 
lated this liquid into a young cow which had calved six 
Meeks before. It was inserted immediately as it was taken 
from the horse into the skin of the teats of the cow. From 
the fifth to the sixth day there appeared transparent vesicles, 
not only on the place of the punctures, but also on other 
parts of the teats and the udder. The seventh, eighth, and 
ninth days these were encircled by a red margin {aureole) 
characteristic of the true pustules. Each vesicle was divided 
into cells containing a limpid serosity, depressed in the 
centre, and forming a scab like the true cow-pox. From the 
fifth to the seventh day the cow presented a slight accession of 
fever, and a diminution of the secretion of milk. Finding 
thus that not only the observations of Loy and Sacco were 
M ell founded, but also the popular tradition in England and 
in Holstein that cows are attacked by the vaccine when 
grease prevailed epizootically amongst horses, it seemed to 
me useless to multiply these experiments."’^ Here are the 
experiments of Mr. Coleman, as they are given in the 
‘ Bibliotheque Britanique.^ Coleman has finally succeeded 
in inoculating a cow with the matter of the grease; which 
inoculation has produced an ulcer on the udder. With the 
virus taken from this ulcer a child was inoculated, which has 
produced well-characterised vaccine.^' For the last twenty 
years there are numerous examples of vaccine produced 
either accidentally or experimentally by the direct transmis¬ 
sion of the matter of grease to man and the cow. Steinbeck 
has successfully inoculated the matter of grease, first, in the 
cow, and secondly, in children. These experiments he has 
repeated both in the cow and in children. The results 
according to Steinbeck, from these experiments is, that the 
matter of grease transmitted to man or to the cow, possesses 
the property of producing pustules similar to those of true 
vaccine, and that the direct transmission to man excites in 
him a febrile reaction, stronger than that of the vaccine; 
that this is modified by passing the equine virus through the 
organism of the cow. Professor Ritter, of Riehl, met with 
an individual in 1830 affected in the hands v-ith exanthema 
taken from a horse that was attacked with grease, and which 
had the closest analogy Mith vaccine. Ritter inoculated two 
children wdth the matter of this exanthema, and in them 
were developed pustules that transmitted the disease to 
other children. No counter-experiments were made. Berndt, 
Professor of the University of Greifswald, visited the groom 
M'ho had pustules on his hands, which he had caught from 
attending a horse with greasy heels. With the matter taken 
from these pustules, several children were inoculated, which 
XXXVI. 33 
