TRANSLATIONS FROM CONTINENTAL JOURNALS. 703 
grease that I did not aceept the fact of Chartres as an evident 
proof of the production of the vaccine from the grease of the 
horse^s legs. I founded my objection on the great number 
of negative results which I had witnessed during the experi¬ 
mental course of M. Bousquet_, and also on the negative facts 
given by other experimentors_, even by Loy, v/ho has not been 
able to produce the vaccine,, he says^ except by inoculating the 
matter from recent constitutional grease. I also founded it 
on the fact that fifteen days at least had elapsed since Brissat 
had been in contact with the horse and the appearance of 
the pustules. This long inoculation of the vaccine is unusual. 
Then the letter of M.Honelbeck had informed me that Brissat 
was affected with phlegmonous erysipelas^ which invaded the 
whole of the back of his hand a fortnight before shoeing this 
horse. Then^ again, I learnt from letters from MM. Honelbeck 
and Bonsergent that the horse shod by Brissat stood in a 
stable with three cows. All these circumstances take from 
this case of Chartres a great part of the value and the im¬ 
portance which has been given to it. Moreover, I have a 
right to be difficult to convince, having seen, during a long 
practice, men of all ages, amongst whom there were no doubt 
many who had never been vaccinated, nor had had the 
smallpox, attend on horses affected with the grease in all its 
stages without being affected with the pustules of vaccine. 
I have never found anything in these men, except, in some 
few cases, herpetic eruptions on the arms and face; the 
same as frequently happens to grooms who attend the 
infirmaries, and are obliged to dress all sorts of wounds and 
sores on horses; these eruptions are altogether local, ephe- 
meric, and without general symptoms. It is probable that 
many of the cases considered as the production of vaccine 
by the grease or other affections of the horse^s legs were 
similar to those eruptions which I have just mentioned. 
It would really be most wonderful to see two maladies so 
different in every respect reproduce each other, when it is 
well known that the malady in question of the horse is not 
infectious from horse to horse; also almost all the cases of 
pretended production of vaccine by the grease have never 
been able to stand the test of a serious scrutiny, or conclusive 
proofs. Those who were supposed to have received immunity 
from the influence of these maladies have not been exempt 
from the attacks of smallpox, or the inoculation of the true 
vaccine; as, for instance, the famous case of Berlin, reported 
by Hertwig, mentioned by Verbeyen, and recalled by Bouley, 
in which it was thought that the vaccine was produced by 
divers maladies^ even by gangrene. I could cite a multitude 
