MINOT : SINUSOIDAL CIRCULATION. 
201 
6 clays:.the liver has acquired considerable volume by the 
growth of the cylinders ; the sinusoids have increased 
in diameter, see Fig. 7. 
11 days: .... the liver is much larger; the sinusoids, except those 
forming the trunks and branches of the system of 
vessels, have diminished in size, owing to the increase 
in number and in diameter of the hepatiq cylinders, 
see Fig. 8. 
Figures 7 and 8 are drawn to the same magnification — 300' 
diameters — so that they may be directly compared with one 
another. Attention is directed to the fact that the blood spaces, 
pass through two phases, since, first , they are small, and then 
Fig. 8. Embryo chick of 11 days. Liver, part of a transverse section; h. c., 
hepatic cylinder ; Si, sinusoid. Harvard Embryological Collection, No. 255. 
gradually enlarge, as correctly recorded by Remak, l. c., and 
second , they are reduced in size by the growth of the cylinders. 
The first phase may be demonstrated by comparing Frobeen’s 
figure, ’92.1, Fig. 4, of the chick liver at 96 hours with my Fig. 7, 
above ; for the second phase, compare Figs. 7 and 8. The sections 
of the various stages show that the hepatic cylinders expand, as it 
were, into the space occupied by the subintestinal vein ; and while 
they expand, the endothelium of the vein forms a close covering 
over the surfaces of the cylinders. There is not a trace of any 
