56 
REPORTS OF OASES. 
membrana nictitans well protruding upon elevation of the 
head, and trismus so far advanced that the incisors could only 
be separated half an inch. Food of a sloppy nature, and 
water could be partaken of sparingly. He was thoroughly 
examined physically, and by inquiry for the presence of 
traumatism ; but history and search revealed nothing further 
than a slight epidermic chafing from a saddle, which pre¬ 
sented no peculiarities, and certainly did not impress me as 
being a point of infection. Under our old methods, I should 
have called this a case of idiopathic tetanus, but in view of 
modern developments we are compelled to recognize its 
microbic origin, and admit that the specific bacteria must 
have gained entrance into the organism, whether through 
this slight abrasion or otherwise. 
I at once placed the patient in a dark box-stall, removed 
the chain fastenings of the other horses, and substituted them 
with rope, administered tartar emetic both in the drinking 
water, and by oral injection. The next morning I saw the 
owner and gave him but little hope of recovery, suggesting at 
the same time a trial of anti-tetanine, to which he assented. I 
procured from the New York Biological and Vaccinal Insti¬ 
tute ten doses of anti-toxine, giving to the Director of that 
institution the above history of the case, and in the following 
recital of its exhibition I have followed his instructions as 
nearly as possible: 
Sunday night , Dec. 29.—Found patient with pulse of 42, 
respirations 54, temperature ioo°. At 8:45, administered two 
doses of 25 cc. each by injection into the jugular vein, and 
four doses of same size hypodermically along the neck, hav¬ 
ing carefully shaved the hair and bathed the skin with anti¬ 
septic solution. Before the injection had become completed 
the patient became excited, which was undoubtedly due to 
the serum, as the puncturing of the skin by the needle caused 
him no uneasiness. In fifteen minutes the excitement was 
considerable, respirations 90 per minute, and pawing with 
front feet. At 9:30, respirations were somewhat slower 
(about 75), of a paroxysmal character; pulse, 46 ; sweating at 
the flanks. I left him for the night at 10 o’clock, free from 
excitement, and on my return in the morning the groom re¬ 
ported that he had remained in that condition throughout the 
night. 
Monday morning, Dec. 30.—Tumefaction at the point of 
jugular injection and one other point, while the remaining 
punctures showed no swelling. Pulse, 42 ; respirations, 64; 
trismus a little more pronounced than on the preceding visit, 
