AZOTURIA. 
123 
scope lucocytes will be seen to contain various numbers of bac¬ 
teria in their interior. In some it would appear that the luco¬ 
cytes were capable of digesting the bacteria and assimilating 
them as nutrition, while in others the opposite suggests itself, 
in view of which the question naturally arises: Do the bacteria 
flock to the lucocytes because they find in them a suitable cul¬ 
ture media, or do the lucocytes make the attack ? 
Those who support the theory of phagocytosis attribute im¬ 
munity to the power of the lucocytes to attack and destroy the 
germ. There is no doubt that they have some such power but 
I do not believe that we can attribute immunity to this one 
factor alone. 
It is well known that the system may acquire a certain toler¬ 
ance to certain drugs, such as opium, tobacco and arsenic. When 
the use of these is continued for some time, doses sufficiently 
large to destroy the life of an ordinary individual may be taken 
with impunity. If the system will acquire a tolerance to the 
action of such drugs it is reasonable to suppose that it may also 
acquire a tolerance to the action of bacteria, or their tox- 
albumins. 
Until more is known on the subject we shall have to be con¬ 
tent with the theory that immunity is due to three factors, viz., 
the action of lucocytes upon bacteria when introduced into the 
body; acquired tolerance of the cellular elements of the body ; 
and the formation in the system of antitoxines which oppose 
further development of the pathogenic micro-organism. 
AZOTURIA. 
By F. S. Allen, D.V.S., Philadelphia, Pa. 
Report of three cases before the Keystone Veterinary Medical Association, March II, ’96. 
On January i, 1887, I was called to see a black gelding,, 
five years old, sixteen and one-half hands high, that was down, 
in a lumber yard, and unable to rise. On my arrival, I learned 
the horse had been removed to the owner’s stable, some four 
miles away, in an ambulance, also that the animal had been 
