American Veterinary Review. 
JUNK, 1896. 
EDITORIAL. 
TUBERCULIN AND MALLEIN. 
Tuberculin. Prof. Nocard is continuing- with enthusiasm 
his propaganda in favor of tuberculin, of its advantages in the 
diagnosis of the presence of tuberculosis in cattle, and of the 
benefit that could be derived from its use in the control of that 
true bovine plague. Our readers have already on various oc¬ 
casions been made familiar with his efforts, his numerous ex¬ 
periments and applications, as well as with the lectures, without 
number, that he has already delivered on those various topics. 
In one of those recent opportunities, after presenting concise 
statistics upon the prevalence of tuberculosis in various parts of 
Europe, relating several instances of the contagiosity of the 
disease ; having shown that to contagion and to it alone was due 
the continuous but slow spreading of tuberculosis, he then urged 
the importance of the use of tuberculin, and concluded his lec¬ 
ture by answering some serious objections which were made 
against tuberculin, and which, having also been made in America, 
we think will prove interesting to our colleagues on this side of 
the Atlantic. Prof. Nocard said : 
“1st. It has been said and written in agricultural journals, that the injection or 
tuberculin might give tuberculosis to healthy animals. 
“It suffices to know how tuberculin is prepared to be satisfied of the inanity of the 
danger. It is true tuberculin is extracted from cultures of the bacillus of tuberculosis ; but 
these cultures, once complete, are first sterilized at the autoctare to no° C., a heat which 
no living being can resist; they are then concentrated in the water bath, to the tenth 01 
their primitive volume; during this operation, which lasts at least two hours, the liquid 
c ture remains to near ioo° heat; then, after filtration, the remaining liquid is diluted in 
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