therapeutic review. 
589 
due to the property of the serum. Indeed, he has taken serum 
from animals that had resisted serious attacks of the disease 
ten or twelve months before. During sixteen days, by daily 
doses he injects to four lambs a total quantity of 190 cubic cen 
timetres and then 14 cubic centimetre of very active variola 
• aTi leSe lambs had no eruption, while a witness, which 
received the same quantity of virus, died of variola. The serum 
there acted as a preventive, but the granted immunity was only 
temporary. In another series of experiments, six lambs received 
a subcutaneous injection of active virus. When the skin beo-an 
L^fV nd r° be “batons at the point of inoculation, 
daily injections of serum are made. The evolution of the disease 
diminishes and is arrested ; the tumor goes down, and a laro- e 
ough takes place, which is eliminated by granulation. There 
7 f\ no “ ldlca tion of generalization. A witness lamb, inocu- 
alHhe'skiWTh TA™ 11 ’ contract <: d a variola, generalized to 
all the skm. Then the serum cures ; but the first injection must 
ik i d !- aS SO °« a v t t 6 a PP ant i° n of the local manifestations of 
inoculation If the local accident is too extensive or if the viru- 
powerfess!-^^ ed th<i Wh0k ° rganiSm ’ the Senlm remainS 
Effects of Maeeein After Injection in the Portat 
f. VS F“ Ify Mm Mr Gtiui(irrf\. — The 
e first to show that the effects of some microbian toxines, in par¬ 
ticular those of pneumobacilline and of the diphtheric-toxine were 
increased by their immediate passage through the liver. Thev 
andlE^T^ thelr f, x P erim f ntS > in usin g the d °S as subject, 
and m employing mallein and tuberculin. The demonstration 
still more marked; as the difference observed in the mani- 
to \ S u he T cal T ed , the lon §: e r life of the animal witness; 
(/A) He had been in j ected in tlle jugular vein.— 
THERAPEUTIC REVIEW. 
Stability of the Solutions of Iodide 
or OF Sodium [By Mr. Carles ] .—To preserve 
these solutions which, with age, become more 
tne author proposed to add to the solutions a 
phite of soda, as follows : 
E. Iodide of potassium, io grammes. 
Hyposulphite of sodae, 0.05 centig. 
Distilled water, 200 grammes. 
of Potassium 
the stability of 
or less yellow, 
little hyposul- 
