. DIABETES MELLITUS IN DOGS. 631 
frequently than before. Appetite good. Urine obtained by 
catheter was pale, but opaque, and held albumen in goodly 
quantities, 1035 specific gravity, and by test gave sugar in 
abundance ; the quantity of urine, however, would not admit 
of thorough quantitative analysis. He was, by request of the 
owner, destroyed, and on rapid examination the thoracic organs 
appeared quite normal. The liver was fully one-half enlarged, 
and of pale, brick-red color, with yellowish tinge ; consistency 
was friable, and on cross section appeared cirrhotic. The aceni 
were well marked off by interstitial connective tissue ; gall 
ducts pervious, and gall sack' moderately filled ; slight duo¬ 
denitis. The pancreas appeared very large and thickened and 
firmer than is usual, and was studded by a few isolated pale 
spots, but which was different from the rest of the organ by 
color alone rather than consistency. The other organs had a 
normal appearance. Abdominal fat much marked. * The cata¬ 
racts were lenticular and quite firmly organized ; indeed, at the 
neucleoli feeling almost cartilaginous. At the margin of the 
spleen was seen a tumor of robin’s egg size, with a smooth cov- 
ering of Glisson’s capsule. This upon closer examination was 
found to be a small hsematoma of long- standincr. 
/TM • . o 
The microscopical examination of the organs, which was 
also followed out in the Virchow Labratorium gave the follow¬ 
ing results : Diffuse fatty degeneration of the entire liver. The 
outline of the aceni being in great part indefinable. Kidneys 
showed granular degeneration of the glomerular epithelium, 
and in patches was entirely absent. There was also similar 
changes noted in the epthelium of the straight tubules. The 
pancreas was very much increased in its connective tissue at the 
expense of the aceni, which were markedly shrunken and the 
epithelium was in part in a state of fine granular degeneration ; 
in other large sections there was a complete change to fat, and 
only in rare cases was it possible to define an apparently healthy 
portion of glandular tissue. 
These comprise the cases seen by me at the clinic, but I will 
refer to another authentic case which I found of interest. 
