284 
EXTRACTS FROM EXCHANGES. 
tablished beyond all question. Bach horse was simultaneously 
injected and watched by a competent observer for a period 
of one and a half hours, a period long enough to allow all 
the effects of the drug to disappear. Three horses received io 
cm. 3 each, two 7 cm. 3 each, one 5 cm. 3 , and one 15 cm. 3 of the 
10 per cent, solution. In all, after from 3 to 30 seconds, twitch- 
ings of the jaw, lasting from 15 to 30 minutes, set in, un¬ 
accompanied by salivation. During all this time, they were 
evidently all ill at ease, for they contracted their upper lips, 
turned and shook their heads vigorously. After from 10 to 150 
seconds, the intestinal action of the drug ensued. The animals 
elevated their tails and passed more or less flatus. Then after 
from 1 % to 3 y 2 minutes they passed without any straining good 
formed faeces. But almost immediately they became restless, 
strained, pawed the ground uneasily, and looked back at tlieir 
flanks. The horse that received 1.5 gm. began to moan and 
strain vigorously, the others in proportion, those with the 
smallest doses hardly moaning or straining at all, one of these m 
fact began to look for food after 4 minutes. Then the discharge 
of gas "and fseces increased, so that during the first hour the 
animals defecated 5, 7, 12, 13, 14, x 4> 26, respectively, the fseces 
at first formed, becoming pasty and then liquid m character. In 
none did salivation or sweating occur. One moaned piteously as 
above stated, one laid down prostrated. In some the borborygmi 
were increased, in others they were diminished. One had 
vesical tenesmus. While none showed a rise in temperature, all 
showed an increased frequency of the pulse, most of them show¬ 
ing an increase of 4 to 8 beats, only one an increase of 36 beats, 
the latter, however, being comparatively quiet. Hence was 
substantiated D.’s claim that Ba Cl 2 affected the heart. But 
this effect upon the heart was only temporary, inasmuch as the 
action of the drug lasted only from ^ to 1 ^ hours, after which 
the circulation became normal again. It is the author s lin 
pression that Ba Cl 2 is more trustworthy and prompt in exciting 
peristalsis without materially or proportionately increasing t e 
intestinal secretion than any other drug. These trial horses not 
being affected with colic allowed of the easy administration o 
the remedy. But in horses rolling about with colic, the proper 
administration of the intravenous injection may be impossible. 
Hence after the lapse of a week, six of these horses were experi¬ 
mented upon subcutaneously, a treatment that may be more 
feasible in colic. Two received 5 cm. 3 each, two 10 cm. 3 each, 
one 15 cm. 3 , and one 20 cm. 3 , of a xo per cent, watery solution 
