306 
review of experimental pathology. 
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with chronic glanders a stronger reaction than in a healthy man 
(about 25 times), viz. : an elevation of temperature after 4 to 7 
hours ; tnrgidity of the conjunctiva and nasal mucous membrane, 
polyuria; as local lesion, a slight, painful and temporary tume¬ 
faction. 2d. The hyperthermia is in proportion to the injected 
mallein (the activity diminishes a little in the following injec¬ 
tions). In the days following, there is an inverse reaction (hypo- 
thermy at 35 5), which lasts 48 hours, without other symptoms. 
Repeated injections of mallein in a glanderous patient, have 
produced a noticeable improvement, but not curative, no more 
than in guinea-pigs, dogs or horses.— {Arch of It. Biol.) 
Regeneration of the Spleen in a Rabbit [By Mr. 
Cere sole]. —The total splenectonomy is well supported by even 
young rabbits ; it does not interfere with nutrition ; but there is 
never"a trace of neoforination of the removed organ. There is 
neither regeneration of the spleen after partial removal .of the 
organ. The left fragment does not increase 111 size, and its par 
enchyma does not appear to be the seat of a greater activity. 
After total or partial splenectonomy no macroscopic change can 
be observed in the lymphatic glands or the bony marrow of the 
healthy animal. The recovery of the wounds of the spleen lea\ es 
a fibrous cicatrix, formed by the proliferation of the fixed cells 
of the reticulum and of the capsula ; which seems to play in this 
process the most important part.— (Rev. Sc. Med.) 
Anti-Anthrax Serum [By Mr. E. Marchoux]. The 
serum of animals (rabbits, sheep) brought by degrees to support 
very strong <Ioses of bouillon cultures of anthrax, obtains a special 
property ; it possesses positive preventive qualities, it is.curative. 
After the injection of this serum, a temporary stimulation is ob¬ 
served in the reaction of the phagocites, which, brings on the 
destruction of the bacteridies. In animals, vaccinated by atten¬ 
uated viruses, they are also destroyed by the phagocites, but with 
them the resistance lasts longer.— (Ibid.) 
A Case of Regeneration of the Spleen [By Mr. Lauden- 
bach ].—After extirpating the greater part of the spleen in a dog, 
the animal was allowed to live with what remained. After six 
months it was found that the organ was entirely regenerated, 
and had resumed the dimensions and structure of. the normal 
spleen. It weighed 17 grammes, while the part which had been 
extirpated weighed 19 grammes, 2.— (Rev. Sc. Med.) 
