INOCULATION AGAINST CONTAGIOUS PLEURO-PNEUMONIA. 
335 
the mouth washed out with acidulated water. During- conval- 
escence I administer iron arsenite, and in danger of heart failure 
I give digitalis. 
The following results have been obtained in the biological 
laboratory at the University of Prague, to determine the germi¬ 
cidal and antiseptic value of the following agents, as tested upon 
this micrococcus: Alcohol, 24 per cent, sol., destroyed the 
micrococcus in 2 hours ; boric acid, a saturated sol., failed to 
destroy it; carbolic acid, 1 per cent, sol., destroys the vit. in 2 
hours ; cupric sulphate, does not destroy ; hydrochloric acid, 1 to 
200, destroys in 2 hours ; iodine aq. sol. with potassium iodine, 
destroys in 2 hours ; mercuric chloride, 1 in 20,000, destroys it 
in 2 hours ; nitric acid, 1 part in 400, destroys it in 4 hours ; 
caustic potash, 2 per cent, sol., destroys it in 2 hours ; potas¬ 
sium permanganate, 2 per cent, sol., destroys it in 2 hours ; 
salicylic acid does not destroy ; sulphuric acid, 1 part in 200, 
destroys. 
PREVENTIVE INOCULATION AGAINST CONTAGIOUS 
PLEURO-PNEUMONIA. 
By E. Biart, V. S., Lansing, Kansas. 
Read before the Missouri Valley Veterinary Medical Association. 
The first really scientific way of preventing the spread of 
contagious diseases among cattle was discovered by Dr. Wil¬ 
lems of Hasselt (Belgium) as early as 1852, but was only 
brought into actual practice at a much later period. 
It was established on a solid basis in his laboratory (the 
stables of a large distillery). The young doctor inoculated di¬ 
rectly into the steer the contagious pleuro-pneumonic virus. 
Injected into the muscle or subcutaneous cellular tissues, the 
germ produced, in addition to the local tumor, phenomena of 
.severe intoxication, from which the animal died in a very short 
time. The doctor then decided to inoculate the same virus at 
the lower extremity of the caudal appendix. There again the 
symptoms soon made their appearance after the insertion of the 
