INOCULATION AGAINST CONTAGIOUS PLEURO-PNEUMONIA. 
337 
and this in all stages of the malady, readily consented. And, al¬ 
though they were kept in constant and close proximity with 
one another for a great length of time, none of the inoculated 
cattle contracted the disease, nor did they show the least incon¬ 
venience. Switzerland and Italy almost immediately accepted 
the system, which afterwards proved effective and of great value. 
The practice is now generally adopted, and in those countries 
wherever employed contagious pleuro-pneumonia is almost a 
thing of the past. In Belgium, where the method originated, 
not a ease has been discovered in the last two years. 
Modus Operandi .—The serum which floats on the expressed 
fluids of diseased lungs in the first or second stages of the dis¬ 
ease, and this must be as fresh as possible, is the right virus for 
inoculation. 
The inoculation is done on the lateral faces of the extremity 
of the tail by two incisions about two inches apart. The skin 
is then raised and a small amount of the serum injected the 
same as vaccination in human practice. A few drops are suffi¬ 
cient. 
The animal may then be turned out without further care ; 
but when local inflammation becomes too intense, from 14 to 20 
ounces of salts must be given. Generally, after ten days of in¬ 
cubation, seldom before, and at the point of inoculation, will be 
seen an inflammatory engorgement, hard, hot and very sensi¬ 
tive, very circumscribed, but, in exceptional cases, extending to 
a vast area of tissue, and this generally becomes gangrenous. In 
ordinary cases this engorgement gives rise to pustules, turning 
out serum and covered with scabs, which dry up, but often 
fall off and leave an ulcerous wound which finallv heals com- 
pletely without care. 
I11 order to have a successful inoculation, these pustules 
should appear ; or at least the inflammatory engorgement. Ani¬ 
mals in whom no reaction has taken place should be reinocu¬ 
lated in from three to four weeks. 
Inoculated animals must be closely watched from the fifth 
or sixth day after the operation, and as soon as tumefaction is 
