354 
EXTRACTS FROM EXCHANGES. 
mur synchronous with the ventricular systole, the well recog¬ 
nized hsemic murmur of anemia not dependent upon any organic 
change in the valves but upon the changed character of the 
blood passing through the valves, in short, an inorganic murmur. 
The temperature varied from ioif° F. to 102-f 0 F. Respiration 
was quickened to 48 per minute. Percussion of the thorax showed 
nothing abnormal with the exception of the increased dullness 
before "spoken of. Auscultation of the lungs showed vascular 
breathing somewhat strengthened. The appetite was good, the 
dejecta dark and thin. The liver and spleen were found upon 
palpation to be markedly enlarged ; . the submaxillary, post 
pharyngeal, supramaxillary and inguinal glands were easily 
felt because of their increased size. Unfortunately I could ob¬ 
tain no urine, gladly as I would have liked to make a urinary 
analysis ; for it would have been interesting to observe whether 
(xanthi, hypoxanthi, guanin, etc.) were present in abnormally 
large quantities. The general behavior was normal ; sensation 
was unimpaired ; the cat was relatively active. In order to sub¬ 
stantiate the diagnosis of leucaemia I examined the blood by the 
Thomazeiss haematositometer ; the blood—taken from the ear- 
even to the eye was of a changed (lighter) color and coagulated 
slowly. 
It took four days to count the red and white corpuscles, the 
average ratio of the red to the white corpuscles being onl} 
twelve to one; amongst the markedly changed and increased 
leucocytes I found multinuclear and mononuclear cells, also 
cells of a hyaline consistency. A large number of red corpus¬ 
cles in their embryonic state were present. These facts may 
perhaps explain why the red corpuscles were so markedly di¬ 
minished in number (olygocythsemia rubra), their number being 
only 300,000 per cubic millimetre. 
I also found a number of needle-shaped (Charcot’s) crystals. 
This blood examination therefore established the diagnosis of 
leucaemia. The animal remained in this same condition for 
about a week and then suddenly died from collapse, with symp¬ 
toms of internal hemorrhage. At the autopsy 1 tablespoon¬ 
fuls of blood were found extravasated under the skin upon the 
left side of the thorax; the abdominal cavity contained two 
tablespoonfuls of an extravasated serous exudate; the perito¬ 
neum showed a greyish white discoloration ; the intestinal canal 
was practically empty, containing a little fluid matter ; the rec¬ 
tum contained feces of a soft consistency ; a half dozen ascarides 
were also present in the bowel. The solitary follicles of the 
