SEEDY TOE. 
609 
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5? 
The experimental work in the college laboratory demon¬ 
strates that fresh cultures of the common pus germs, under 
different conditions produced different forms of septic infec¬ 
tion. The work with the staphylococcus pyogenes, varieties 
aureus and citreus, was partly to determine the length of time 
the germs retained their virulence. With the aureus, three 
generations, embracing a period of nine months, was sufficient 
to destroy its virulence. With the citreus, four generations, 
embracing a period of nine months, was sufficient to destroy 
its virulence. Experiments with the streptococcus pyogenes 
to determine the time it retained its pathogenic properties 
demonstrated that two generations, embracing a period of five 
months, was sufficient to destroy its virulence. Such experi¬ 
ments prove that continued cultivation outside the animal body 
destroys the pathogenic properties of the germs of sepsis, al¬ 
though they retain their physical powers of development. 
“ SEEDY TOE.” 
By W. Bkyden, Y.S., Boston, Mass. 
(A paper read before the Massachusetts Veterinary Medical Association). 
About fifteen months ago I was called to examine a lame 
lorse, one of a handsome pair of grays, used on the engine of 
:he fire department at Medford, a pleasant town situated 
>ome five miles from Boston. They were a well-matched, 
licely trained span of strong, speedy horses, some ten or 
deven years old, fifteen hands three inches high, and weighi¬ 
ng about fourteen hundred pounds each. Being general 
avorites, it was ill news for the boys when they learned that 
)ne of their splendid gray fire team was seriously lame. 
On examination of the derelict foot (the off fore one), the 
lisease was found to be what is generally known as “ seedy 
oe.” It had evidently been affected for many months, gradu- 
illy showing greater brittleness of the lower part of the wall 
md of the sole in front. Indeed, the characteristic retrograde 
changes in the horn at the coronet in front, and its separation 
ind projection nearer the toe proclaimed the foot a victim of 
