American Veterinary Review, 
SEPTEMBER, 1892 . 
EDITORIAL 
Tuberculine, Malleine, Morvine. —The announcement 
iof the discovery of tuberculine, with the recommendation of 
its utilization as one of the most valuable of assistants in vet¬ 
erinary diagnosis in cases of doubtful bovine tuberculosis, is 
an occunence of comparatively recent date. Opinions are 
still at variance, however, as to its positive value, the experi¬ 
ments of Dr. Arloing seeming to prove that the characteris¬ 
tic reaction is not always reliable, while, according to other 
authorities, and among them Professor Nocard, the subcu¬ 
taneous injection of the substance in question has bv a long 
series of experiments established its claim as an almost posi¬ 
tive means of diagnosis, by the febrile reaction and elevation 
of temperature accompanying it. 
The discovery of Professor Koch was the preliminary of 
others, since it was inferred that if such a product could be 
obtained from the culture of the bacillus of one among the 
:ontagious diseases, other and similar affections would, in all 
probability, be found subject to analagous laws. And it was, 
ndeed, but shortly afterwards that the announcement was 
nade of the claim of Hellmann and Kolningand Preusse that 
hey had obtained from the cultures of the bacillus of gland¬ 
ers a special substance to which they gave the name of mal- 
eine, and for which they claim, among other properties, that 
of causing a rise of temperature similar to that following the 
noculation of animals affected with glanders. 
