EXTRACTS FROM FOREIGN PERIODICALS. 
321 
EXTRACTS FROM FOREIGN PERIODICALS. 
(Translated from German Papers by Richard Middleton, D.V.S., 
Philadelphia, Pa.) 
VALUE OF MALLEINE. 
From the results of our experiments we consider it impos¬ 
sible to successfully refute the statement concerning the 
pecihc action of malleine upon horses affected with glanders. 
Though administered to healthy horses and to others afflict¬ 
'd with diseases other than glanders, these failed to manifest 
in advance in the temperature. 
Before entering more minutely upon a description of the 
ymptoms provoked by injections of the virus in glanderous 
quidas, we wish to state, respecting the reaction of tempera- 
ure, that we have only taken notice of increase of at least i ° C., 
^hen making up the several tables given in our experiments, 
besides the augmentation of the body temperature following 
r 
he inoculations, the afflicted horses evinced decreased cere- 
ral activity, together with accelerated pulse and respiration, 
t few horses exhibited faintness after the treatment, and a 
lore or less complete loss of appetite. The alterations 
/hich appeared upon the point of insertion of the needle 
fere unusually variable. In most of the cases there formed 
n inflammatory swelling the size of a hen’s egg, which in the 
allowing days disappeared. 
In other cases the local reaction of the virus upon gland- 
rous animals seemed more prominent (since malleine is an in- 
onstant preparation respecting its chemical composition, the 
ariations here noted may be referable to this fact). The 
rinciple clinical symptom, the fever, as we have repeatedly 
mphasized, happens in glanderous horses immediately after 
le injection. An apparent exception to this rule was seen in 
fo. VIII., which we treated three times with malleine, and 
hich gave the fever reaction only after the third injection. 
Upon section of this animal we discovered an old gland- 
*ous nodule in the lungs. The experiment of inoculating a 
uinea-pig with this nodule gave a negative result; since, 
