PATHOLOGICAL ANATOMY. 
390 
PATHOLOGICAL ANATOMY. 
HISTOLOGICAL STUDY OF THE EXPERIMENTAL AND SPONTANE¬ 
OUS TUBERCULOSIS OF THE LIVER. 
By Pilliet. 
Aviar tuberculosis saves rise to lesions liable to consider- 
o 
able variations. In the rabbit one may observe either an 
absence of extensive lesions (that is, massive) or the formation 
of giant intra-vascular, surrounded with embryonic cells 
(Yersin type), or again, the formation of giant cells of transi¬ 
tory duration, which become the origin of an acute tubercu¬ 
lar cirrhosis. In the guinea pig, the last form is most pre¬ 
dominant. In birds (in spontaneous cases), the lesions vary, 
amyloid transformation being more frequent in some, while 
absent in others. 
Experimental human tuberculosis gives rise, in the guinea- 
pig and the dog, to generative lesions (even of coagulation), 
which may resemble caseous tuberculosis, and to inflammatory 
lesions of an interstitial hepatatis, which obliterates the cap¬ 
illaries, and stimulates, secondarily, the atrophy of the haben¬ 
ulae with its sequelae. In the acute forms, no properly so- 
called tuberculosis is found in the liver. One may find in that 
organ in man, nodular lesions, not encysted, lymphoid in their 
nature, and often accompanied with hemorrhages, and form¬ 
ing a starting center for cirrhotic lesions. There is no essen¬ 
tial difference between these lesions and those which are pro¬ 
duced in the guinea-pig. In the monkey, intermediate forms 
are found. 
The existence of this series of intermediate forms between 
the most marked cases, renders the appreciation of the nature 
of the inflammatory or degenerative lesions difficult; and it 
is here that anatomo-pathology must be enlightened by 
pathogeny.— Rev. des Sc. Med. 
EXPERIMENTAL RESEARCHES IN THE TRANSMISSIBILITY OF 
THE CANCER. 
By S. Duplay. 
The attempts which have been made to transmit cancer 
from the dog to other animals (rabbits and guinea-pigs), or 
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