82 
JAMES LAW. 
primary danger of death by the chemical poison, it died in the 
course of about two days of bacteria infection and the blood 
was found swarming with bacteria. Similarly Chauveau found 
the Algerian sheep, that are naturally insusceptible to anthrax 
and which successfully resisted inoculation with a minimum 
amount of the virus, fell victims to the disease, if an excess of 
the poison were injected under the skin, or if a second and third 
inoculation were practiced before the effects of the first had 
passed off. Finally Cossar-Ewart, and Burdon-Sanderson found 
that when anthrax liquids had been devitalized by exposure for 
some time to compressed oxygen (12 atmospheres)and when the 
germs had lost their power of propagation and increase, the 
fluid still proved injurious, and even fatal to animals on which 
it was inoculated. With the vital germ destroyed these evil 
effects could only come of the remaining chemical poisonous 
products, which retained their original potency. 
“ My own experiments with the virus of hog-cholera tend 
to establish the same fact in that disease. When I had subject¬ 
ed the virulent fluids for an hour to a temperature oscillating 
between 130° and 140° F., and then inoculated them on the 
pig, I found that the result was a certain amount of constit¬ 
utional disorder and ill health, which did not, however, go on 
to a fatal issue. * * * Similarly when I injected into the 
system large quantities of the virulent fluids, 1 found that death 
took place almost without exception, even in animals that had 
resisted ordinary inoculations. Of this mortality we may find 
an explanation in the febrile state of the system induced by 
the presence of the chemical poisons. * * * Itisnotthe 
increase in the number of the bacteria alone, nor the access 
of fresh, and therefore more potent germs, that have the evil 
effects, for in the infected system there is practically no limit 
to the multiplication of the bacteria, and these, in place of 
being weakened, are often rendered more potent by passing 
through a succession of animal systems. * * * 
“' Is future protection secured by the action of the chemi¬ 
cal products alone, or is the presence in the system of the bac¬ 
teria essential?’ Under this head are discussed the doctrines 
of immunity by elimination of systemic products necessary to 
