90 
JAMBS LAW. 
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quired by the living tissues by continuous exposure to the 
action of the poisonous ptomaines, he specifically denies the 
possibility of any profit from the use of small doses of the 
latter. On page 310 of the Department Report he says : “ That 
this method was entirely inefficient, however, was completely 
demonstrated, and the conclusions of Toussaint and others 
shown to depend on wrong interpretations of the facts ob¬ 
served.” 
DR. SALMON’S SUCCESS WITH SWINE-PLAGUE. 
Dr. Salmon seems to have returned to this method in De¬ 
cember, 1885. In a paper read before the Biological Society 
of Washington, Feb’y 20th, 1886, and contributed by Drs. 
Salmon and Smith, these gentlemen record their experiments 
on six pigeons with swine-plague virus sterilized by heat (50° 
C. for ten minutes). One pigeon (No. 8) which was infected 
with 8 cc. of the heated culture fluid, and fifty-one days later 
it was inoculated with 75 cc. of strong swine-plague virus, with 
the result that it died in forty-eight hours. A second pigeon 
(No. 10,) was injected with 4 cc. of the heated virus, and on 
three subsequent occasions at intervals of twenty-eight, eight 
aud eight days it had an inoculation of 15 cc. of similar heated 
virus, and on the seventh day succeeding the last injection it 
had an injection of 75 cc. of strong virus, but remained well. 
The other pigeons had injections of 15 cc. of the heated virus 
on three occasions, with intervals of eight days, and a third had 
two injections of the same amount with an interval of sixteen 
days, and seven days after the last each was injected with 75 
cc. of strong virus, but all remained in good health. Finally a 
check pigeon which had not been injected with the heated 
virus was the same day with five odiers injected with the 
same amount (75 cc.) of strong virus and died in twenty-four 
hours. They thus sum their conclusions:— 
“1 st, Immunity is the result of exposure of the bioplasm of 
the animal body to the chemical products of the growth of the 
specific microbes which constitute the virus of contagious 
fevers. 
“ 2d, These particular chemical products are produced by 
