190 
JAMES LAW. 
accult and chronic forms of the disease saves the operator 
largely from the dangers that beset him in such affections as 
lung plague and hog cholera. 
EXPERIMENTS WITH RABIES. 
ist. April 2, 1886, I injected hypodermically in the back 
of a rabbit (No. 1.) ten drops of a lactescent fluid made with 
the brain of a man who had died of hydrophobia March 30th. 
May 18th the same rabbit was again injected hypodermical¬ 
ly with brain matter of a dog which died May 17th of rabies. 
June 14th (seventy-two days after the first inoculation) this 
rabbit was found paralyzed, the paralysis increasing the two 
following days, so it was killed June 16th and utilized for 
further inoculations. 
2d. April 3d I injected on the left cerebral hemisphere of 
rabbit No. 2 the same fluid (from the human brain) used in 
No. 1. Rabbit Avas dull for three days, but ate its food. 
After this it seemed well and lively up to the 18th inclusive. 
April 19th in the morning it was paralytic but still fed. April 
2ist the paralysis had become complete, and the body was 
becoming cold. At 4 p.m. it was found dead. The attack 
came on on the 16th day after inoculation, the regulation 
time for rabies resulting from inoculation on the brain. 
3d. April 3d I injected a black and tan terrier, No. 3, in 
the flank with twenty drops of the same fluid used for Nos. 
1 and 2, but which had been heated for an hour to a temper¬ 
ature ranging from 150° to 180 0 F. April 19th and 20th two 
other inoculations were made in the flank with the same 
sterilized liquid as before. April 22d an inoculation was 
made on the cerebrum of a milky fluid made by mixing a 
portion of the medulla oblongata of rabbit No. 2, which died 
the day before, with boiled water. 
May 17th the dog which had lost appetite for several 
days snapped at a stick and later at my leg. It was found 
dead next morning. It is noticeable that twenty-five days 
elapsed before symptoms appeared. The rule is that after 
inoculations on the brain symptoms set in in fifteen days ; it is, 
therefore, reasonable to infer that the first inoculation with 
sterilized virus had conferred a partial insusceptibility. 
