322 
Gr. A. JOHNSON. 
the remedy, on account of the severity of its local action upon 
the digestive tract. To obviate this he recommends the sub¬ 
cutaneous injection of sodium cantharidate in the region of 
the spinal column ; the dose is one to four drachms for an adult 
man. 
During such a course of cantharides, the urine must be 
kept under constant surveillance ; the moment blood corpus¬ 
cles or cylinders are detected the agent is to be immediately 
discontinued. 
Success in some cases has been ascribed to this new 
therapy. 
The commercial sodium and potassium cantharidate are 
not to be used, from the fact that the gradation of the dose is 
impossible. Preferably, one dissolves 0.2 grains of canthari- 
din in 0.3 grains of sod. hydrat. and heats the same to¬ 
gether with 20 ccm. of aq. distillat over a water-bath until 
there is a clear solution; while the latter is still warm it is 
added to sufficient water to raise the total to exactly one liter. 
One cubic centimeter of this solution represents 0.0002=2 dgm. 
of sod. canth. 
OPEN-JOINTS, AND A NEW REMEDY. 
By G. A. Johnson, D.Y.M., Odebolt, Iowa. 
(A paper read before the Western Iowa Veterinary Medical Association). 
I will offer for your consideration this evening the subject 
of open-joints, and in connection with it a short discussion of 
the new remedy, aniline. 
Open-joint is an affection often met with in this section of 
the country as a sequel to barb-wire injuries, and is always of 
a serious nature, but does not, as of old, necessitate the de¬ 
struction of the animal. 
It is needless for me to take up your time with a discus¬ 
sion of its symptomatology and pathology, so 1 will at once 
take up the line of treatment. 
The first, greatest, and in fact the base of all treatment is 
cleanliness, surgical cleanliness, which consists in thoroughly 
disinfecting the joint and wound, and to maintain aseptices, 
