koch’s tuberculin. 
433 
Ihe autopsy showed a well marked miliary tuberculosis, and 
numerous abscesses throughout the lung, varying in size from 
one-quartei to half an inch in diameter, filled with cheesy pus. 
The mediastinal glands were several times larger than normal 
and had entiiely broken down into a cheesv mass. 
Evidences of lobular pneumonia were found in different 
parts of the lung. The general distribution of these lesions 
indicated an active stage of tuberculosis. 
These facts certainly.indicate that the tuberculin had no 
effect in curing the disease or even in arresting its progress. 
Case No. 2. —This was a five-year-old cow, weighing 
about 700 lbs. When taken into the hospital her temperature 
was iQ4f°, pulse 114 and respiration 48, shallow and painful; 
from this time the temperature began to decrease, the pulse 
and respiration remaining unchanged. The animal died four 
days after admission, but, twenty-four hours before death, 
received 100 mg. of tuberculin, from which no reaction 
resulted. Autopsy showed traumatic pericarditis and pleurisy, 
no evidences of tuberculosis. 
Case No. 3.---This was a roan cow eighteen years old and 
well nourished ; supposed to be healthy with the exception of 
a slight chronic bronchitis. Temperature, pulse and respira¬ 
tion were normal. The injection of 100 mg. of tuberculin 
produced no reaction. After an interval of one week, 500 mg. 
were injected without producing a reaction. At the expira¬ 
tion of another week, March 25th, 1,000 mg. were injected; 
twelve hours afterward the temperature had risen to 104°,’ 
thus furnishing a typical reaction. It was noticed that when 
a marked reaction occurred the temperature remained per¬ 
manently higher than before ; in this case, instead of dropping 
to normal, it fluctuated between ioi°and 102°. On the 4th of 
April this cow again received 100 mg. of tuberculin, with no 
reaction. 
The autopsy showed very little change on the exterior of 
the lung , section of this organ, however, revealed miliary 
tubercles disseminated throughout the lung substance. The 
anterior and posterior lobes of both lungs contained several 
abscesses varying from the size of a hazel nut to that of a 
