470 
EXTRACTS FROM FOREIGN JOURNALS. 
THE BACTERIOLOGY OF GLANDERS. 
From a careful study of this subject Dr. Finger, of Vienna, 
has arrived at the following conclusions: Successive local in¬ 
jections of the bacilli of glanders into animals susceptible to 
the poison produce with each injection symptoms of gradu¬ 
ally diminishing virulence—that is to say, the first injection 
only produces the typical nodules, the later ones causing an 
abortive type of the disease. 2. The constitutional symptoms 
of glanders after intravenous injection of virulent cultures 
produces an incomplete local immunity, and an abortive 
course after subsequent local injections. 3. Intravenous in¬ 
jection of virulent cultures quickly causes death in some ani¬ 
mals—sometimes in a few hours ; in such cases post-mortem 
examinations fail to discover any local manifestation of the 
disease. 4. Intravenous injection of a sterilized culture of the 
bacilli of glanders produces in rabbits an immunity against 
the infection from pure cultures which lasts from three to six 
weeks. Local manifestations, however, occasionally appear, 
these being of an incomplete nature and not followed by any 
constitutional symptoms. At the end .of the above-named 
period, however, the injections are followed by a typical 
and rapidly fatal disease. 5. Rabbits which have survived an 
ordinary attack of the disease enjoy afterward complete im¬ 
munity. Repeated local injections simply produce a transi¬ 
tory local affection, constitutional symptoms never following. 
6. This immunity does not appear to be able to be transferred 
to the offspring—that is to say, does not become hei editary. 
7. The injection of sterilized cultures of the bacilli or of their 
chemical products produces poisonous effects, generally mild 
in character, but sometimes so severe as to kill the animal. 
Post-mortem examination reveals the same lesions as are seen 
in the primary disease, localized mainly in the portal system. 
8. Injections of sterilized cultures produce an immunity, 
though not always complete, against intravenous injection of 
virulent cultures. 9. If sterilized and virulent cultures are in¬ 
jected at the same time, the disease produced is exceedingly 
rapid and fatal. 10. The bacilli when introduced into the 
