experiments with glanders lymph. 
499 
region, inflammation of the carpal joints, and nasal discharge. 
Its condition continued to deteriorate from day to day, finally 
necessitating its death. The post-mortem revealed numerous 
subcutaneous abscesses, suppurative arthritis, and ulcers of 
the septum nares. 
At the beginning of June, this year, another opportunity 
offered to test the malleine upon equidte. On a certain farm 
in the district of C-, commencing in April, there were 
eleven horses; five of these, afflicted with glanders, were 
killed. We lound, together with recent alterations of the 
mucous membrane and small nodules, also quite old caseous 
and calcified collections in the liver, lungs and spleen; mant^ 
old cicatrices were visible throughout the respiratory track, 
so that we were justified in dating the origin of the disease 
over one year back. Shortly after this one of the surviving 
mares met her death from a wound, and was also discovered 
to be glanderous. This mare had, some time previous, given 
birth to a foal, which, together with the remaining five horses 
not any of them having shown suspicious symptoms—was 
killed. 
Through the kindness of the owner, I was given permis¬ 
sion to institute some experiments, and arrived at the farm 
one day previous to the time set by the police authorities for 
their death. 
I took one part of lymph, between three and four weeks 
old, and carefully sterilized ; to this I added ten parts of a 
two per cent, carbolic solution, as a further means of killing 
any bacilli which might exist in the same. The horses used 
were: 
No. i. Brown gelding, four years old, medium well nour¬ 
ished, short cough, but otherwise apparently healthy. 
No. 2. Sorrel mare, nine years old, medium well nour¬ 
ished, with short, sharp and raw cough. 
No. 3. Sorrel mare, eight years old, medium well nour¬ 
ished, with weak cough. 
No. 4. Sorrel mare, fifteen years old, lachrymation of left 
eye with excoriation of the skin inferior to same. 
