SNAKE BITE AND ITS ANTIDOTE. 
271 
12:15 p.m.— The pigeon died without a struggle. 
In tliis experiment the permanganate solution was injected 
twice in the immediate vicinity of the venom injection. It should 
I not be forgotten that the 1 per cent, solution of the permanganate 
is the one recommended by de Lacerda. 
Oct. 25—12:45 p.m. —Injected a large healthy English rabbit 
in the left thigh with 5 minims of the venom solution, followed 
at once, without removing the hypodermic needle, with an in¬ 
jection of 25 minims of the 1 per cent, permanganate solution. 
12:50 p.m.— .Rabbit began to show the effects of the venom; 
respiration very much quickened; heart beats fast and is weak; 
animal indisposed to movement. 
1 p.m.— Rabbit drank a little water, but was breathing 
short and fast. 
1:10 p.m.—P art injected quite swollen and ecchymosed, but 
otherwise the animal seemed to be better. 
1:40 p.m.— Rabbit was eating, and appear to be doing very 
well. 
3 p.m.— Rabbit seems perfectly well with the exception of a 
stiffness of the leg injected. 
Oct. 26—12 m.— Rabbit appears perfectly well with the excep¬ 
tion of a slight lameness and some swelling of the injected leg. 
Oct. 27 Rabbit found dead in the cage. Post mortem: 
Heart contracted, lungs, liver and kidneys congested, bladder full 
of urine, intestines full of faeces. In the vicinity of the point of 
injection was found a large abscess, and the surrounding tissue 
and the whole limb was ecchymosed, and had sloughed deeply. 
The liver, lungs and mesentery were studded with parasitic cyst 
worms still living. Decomposition was well advanced in the 
affected leg. 
In the next experiment it was decided to use a smaller dose 
of the glycerine-venom, the subject being a large healthy English 
rabbit. 
Oct. 27—11:45 a.m. —Injected rabbit in left thigh with 3 
minims of venom solution, to which was added 10 minims of water 
without withdrawing the hypodermic needle; this was followed 
at once with an injection of 25 minims of 1 per cent, permangan¬ 
ate solution. 
