SNAKE BITE AND ITS ANTIDOTE. 
273 
Nov. 5—Fowl suffering no inconvenience from the injection ; 
discoloration of the part subsiding; very little swelling. 
Nov. 6—No result. 
Nov. 7—Discoloration and swelling of part injected have 
entirely disappeared and the fowl has entirely recovered from 
the effects of the venom. 
It will be seen from this experiment that the permanganate 
had a decided antagonistic effect to the venom, doubtless because 
the ligature confined the latter to a limited area, and prevented it 
being carried into the general circulation. In the next experiment 
the venom solution and permanganate were mixed together and 
used with the result as noted below. 
Nov. 3—12:10 p.m. —Injected into the right leg of a fowl 3 
minims of glycerine-venom, 5 minims of water and 30 minims of 
1 per cent, solution of permanganate, mixed in vessel and allowed 
to remain together two minutes. Solution of permanganate 
changed at once to a color, resembling solution of dragon’s blood. 
Nov. 1—Fowl appears to suffer no inconvenience from the 
effects of yesterday’s injection. Slight swelling and discoloration, 
and only a slight increase of temperature. 
Nov. 5—Fowl as well as ever. 
Nov. 7—Discoloration of and swelling of the partpnjected has 
disappeared, and the fowl is in a perfectly healthy condition. 
With a view to still further determining the beneficial effect 
of the ligature, the following experiment was tried with a large 
dose of the venom and of the permanganate: 
Nov. 10—12:45 p m. —Injected 10 minims of venom solution 
into right leg of hen below ligature, followed at once by 25 minims 
of 2 per cent, solution of potassa permanganate. Ligature allowed 
to remain on three minutes. The tissues near puncture were well 
kneaded. (This chicken was injected before with 3 minims of 
venom and 1 per cent, solution permanganate.) 
2:30 p.m. —Fowl inclined to stand still, otherwise no other 
symptoms noticed. 
Nov. 11—11 a.m. —Fowl not inclined to move around, but 
sits down ; not much swelling or inflammation of the part injected, 
but a little darkened in color; eats well. 
