274 
H. C. YARROW. 
2:30 p.m. —Fowl appears to be much better than she was this 
morning; eats and drinks as usual. 
Nov. 12—11 a.m. —Fowl slightly lame in the leg injected ; 
part swollen, with greenish discoloration; eats and drinks well. 
2:30 p.m. —Fowl in same condition. 
Nov. 13—No result. 
Nov. 14—Fowl entirely recovered. 
It was thought advisable to try the antidotal effect of a much 
stronger solution of the permanganate, giving a small dose of 
venom, the result being as follows: 
Nov. 21—12:18 p.m. —Injected 3 minims of venom solution 
into left, leg of hen, followed at once by 25 minims of 5 per cent, 
permanganate solution through the same puncture without re¬ 
moving the canula. 
12:22 p.m. —Leg drawn up and trembling; respiration quick¬ 
ened, and chicken lying down—can hardly be made to stand up 
and oscillates backward and forward, feathers ruffled. 
3 p.m.— Chicken will not stand, loss of motion of leg injected. 
Nov. 22 — 11 a.m. —Chicken somewhat better, can use leg in¬ 
jected a little, but still inclined to lie down. Much swelling and 
greenish discoloration of the leg. 
Nov. 23—Hen in about the same condition as yesterday. 
Will not stand up. 
Nov. 25—10 a.m. —Hen found dead; much swelling and 
sloughing of the leg injected. 
This same experiment was repeated upon other fowls and 
upon rabbits, the result being death. 
It should be remembered in this connection that de Lacerda 
claims that in nearly every case in which he used a 1 per cent, 
solution of the permanganate the animal recovered, and moreover 
he claims that the antidotal effect is produced even if a consider¬ 
able period of time has elapsed after the injection of the venom. 
In our experiments we have shown that even a 5 per cent, solu¬ 
tion is of no value, and the reputed antidote was used imme¬ 
diately after the injection, in fact so soon as the venom was in¬ 
jected the barrel of the hypodermic syringe was immediately 
/Unscrewed from the needle which was allowed tg remain imbedded 
