344 
W. L. WILLIAMS. 
thighs, of lenticular pustules, succeeded by readily healing ulcers, 
but no such eruptions have occurred in the present outbreak. 
There does occur , however, in a large proportion of cases, a 
pecular loss of pigment in the skin of the vulva, perinseum and 
anus, beginning usually in spots of variable size and shape, grad¬ 
ually enlarging and coalescing until the entire vulva, perinseum 
and anus may be one continuous white patch, with irregular bor¬ 
der, or dotted over with white spots varying from one-fourth to 
one inch or more in diameter. The vaginal discharge may vary 
greatly in amount and may cease after a few months, or may per¬ 
sist for a year or more, is usually dirty white or grayish in color, 
frequently possesses an offensive odor, becomes viscid and glutin¬ 
ous, adhering to and irritating or excoriating the adjacent parts. 
Coitus increases the vaginal discharge, as well as aggravates 
in every way the symptoms of the disease. In many cases there 
is a marked loss of power in the vulva and vagina, causing an in¬ 
voluntary discharge of accumulated matter from the vagina during 
sudden exercise. 
Incontinence of urine has been noted in a well-marked case of 
fifteen months' standing, which added to the catarrhal discharge 
and, adhering to the tail and thighs, made a very repulsive sight. 
The most constant and persistent symptoms noted in the present 
outbreak are the changes in the vulva and clitoris. 
The margins of the vulva lips lose their black pigment early 
in the disease, and is not replaced until after the white spots on 
the external parts of the vulva, on anus, perinseum and under side 
of tail have wholly disappeared, which usually occurs after six or 
eight months. The vulva shows a marked tendency to gape, espe¬ 
cially at its lower commissure, due partly, doubtless, to a loss of 
power in the vulva itself, but mainly to the enlarged clitoris push¬ 
ing the lips apart; this gaping giving the appearance of extreme 
age to a young mare. The clitoris is quite uniformly enlarged, 
exhibiting a smooth shining surface, wholly devoid of pigment and 
unnaturally dry, there appearing to be a destruction of the mucous- 
secreting glands of the clitoris and fossa navicularis, or at least a 
temporary destruction of their secreting power. 
Infected mares rarely conceive, and the few that do almost 
