RATTLE WEED OR LOCO-DISEASE. 
went upon another horse and procured a bushel of the pods of 
that plant, and gave daily an infusion obtained from about one 
, quart | o the pods. On the fifth day of the experiment the 
e laracteristie stupor came on and grew more marked until the 
thirteenth day, when the animal died. The post mortem examination 
gave again the regular result. Prof. Stalker, now State Veteri¬ 
narian m Iowa, calls this disease crotalism, from the name of the 
plant, Orotalaria Sagettalis, which belonging closely to the same 
ramily and species of plants, will make no difference as to the 
real cause of the rattleweed disease, and this is proven to satis- 
taction by the above experiments. 
Let us pass now to the pathological lesions after death. As 
1 never had any opportunity to make a post mortem examin¬ 
ation of the disease myself, I cannot give any opinion as 
to the nature of these lesions, but I refer to the results pub- 
hshed in the Review by two competent veterinary surgeons. 
ror. fe talker made the after-death examination of five subjects 
with the most perfect uniformity as to the lesions presented. In 
every instance there was a marked infusion into the fourth ven¬ 
tricle of the cerebrum; liver and spleen were abnormally dense, 
the walls of the intestines almost destitute of blood and the 
stomach enormously distended with undigested food ; the stomach 
with its contents weighed as much as seventy-five pounds. 
In the July number, 1888, of the Keview, .Dr. Schwartzkopf 
Veterinarian in the United States Army in Western Texas* 
states that he found the large sinuses of the cerebrum to be 
filled with straw-colored fluid ; the vessels of the pia-mater in¬ 
jected; the gray brain substance reddened and oedamatous, and 
the cut surface glistening and moist. On the basis of the brain, 
inside the arachnoids, about one teaspoonful of pinkish fluid; 
the medulla oblongata and parts of the spinal cord taken from 
cervical and lumbar regions oedematous in appearance and moist 
incut surface; thoracic cavity normal; heart endocarditic in a 
slight degree, stomach partially filled with ingesta; abdominal or¬ 
gans all normal. 
■Physiological Remarks Concerning the Nature of the Disease. 
—According to these lesions, which I consider to be very clear 
