CASE REPORT OF INTESTINAL CALCULI. 
497 
of sulphate of morphia, combined witli a quarter of a grain of 
sulphate of atropia and gave another enema. No further symp¬ 
toms of pain were observed during the balance of the day. Wed¬ 
nesday morning, December 12 th, found the mare suffering severe 
pain, the paroxysms occurring more frequently; bowels still un¬ 
moved. Gave 3 i of aloes, 3 i fluid ext. nux. vomica, 3 i fluid 
ext. belladonna, fifteen minims of fluid ext. capsicum, applied 
blankets wrung out of hot water to abdominal region and admin¬ 
istered another enema. Repeated the hypodermic injection of 
morphia and atropia, which again appeared to afford the animal 
gieat relief, which continued during the rest of the day. Thurs¬ 
day morning, December 13th, found the mare’s condition as fol¬ 
lows: Temperature, 1021 °; pulse, 60 ; respirations, 20 ; increased 
abdominal tension, almost continual pain ; bowels still unrelieved. 
Suspecting the presence of calculi, called in Dr. William 
Dougherty for consultation. That gentleman considered the 
case to be one of mechanical obstruction due to the presence of 
a calculous deposit in the intestines, and advised that a trial be 
made, of the eserine and pilocarpin treatment. Accordingly at 
ten o’clock Thursday morning he administered one and a half 
grains of eserine combined with two grains of pilocarpin. The 
following effects of the medicine were noted: profuse salivation 
ensued in twelve minutes; first discharge from the bowels in 
forty minutes ; second in fifty-two minutes; third discharge in 
two hours. After that the cathartic effects of the medicines 
giadually diminished: the usual physiological action of pilocarpin 
on the skin was but feebly marked in this case. Six hours after 
the administration of the medicines the temperature was reduced 
to 101i°; pulse, 48; respirations nearly normal and no apparent 
pain. From that time forward the mare’s condition varied from 
day to day. She lingered along until the 28th day of December; 
during that time her treatment was chiefly directed towards the 
symptoms as they presented themselves. At ten o’clock on the 
night of December 28th, it being the eighteenth day since her re¬ 
ception at the hospital, she looked brighter and more cheerful 
than she had for several days previous ; temperature, 1011 0 ; pulse, 
47 ; respirations tranquil; she drank some oatmeal gruel. Next 
