500 
W. R. HOWE. 
treatment of this disease; it lessens or overcomes the spasms and 
improves the action of the bowels. It is in cases of indigestion, colic, 
flatulency from any cause, obstinate constipation, azoturia, or 
almost any case where it is necessary to get a prompt action of 
the bowels, where this drug is of most value to the veterinarian. 
In acute indigestion in the horse, a hypodermic injection of from 
one-fourth to three-fourths grain, according to the patient and 
case, relieves the pain by overcoming the spasmodic condition, 
stimulates the flow of the gastric secretions, thus aiding digestion, 
stopping fermentation, and stimulates natural peristalsis even 
when the bowel is paralyzed by distension, thus promptly evacu¬ 
ating the bowels, not only of faeces, but flatus, and removing not 
only the cause of the trouble but the trouble itself, in less time 
than by any other known treatment. In constipation, if given in 
small repeated doses, will often give complete relief. I have had 
excellent results in treating azoturia with this drug by giving one 
grain and following with one-half grain doses every half hour 
until the bowels moved freely; it not only evacuates the bowels, 
but relieves the spasmodic condition of the glutial muscles in from 
one to three hours in moderate cases. I have used it in several 
cases of immobility to evacuate the bowels, which it has never 
failed to do. There is generally considerable improvement of 
the other symptoms, but I always follow it with philocarpine in 
about fifteen grain doses hypodermically, generally with pleasing 
results. I have never combined eserine with philocarpine. 
Where a cathartic has failed to act in time, a hypodermic of 
eserine will generally bring about the desired result. To dogs suf¬ 
fering from fits caused by constipation, one-thirtieth to one-tenth 
grain hypodermically will often give complete relief. 
In parturient apoplexia in cows it appears to give relief, but 
so far as ray experience has gone it has been merely temporary, 
as it appears to soon lose its effects. JDrs. J. M. Weaver and C. 
C. Meyers, both physicians of good standing in Dayton, Ohio, 
report that they have used eserine with excellent results and 
prompt relief, where other remedies had failed, in flatulency fol¬ 
lowing child-birth. 
The great object in advocating this drug in the treatment of 
