508 
H. C. YARROW. 
2:30 r. m. —Chicken still lying down and breathing fast. 
Nov. 29—11 a. m. —Chicken in same condition as yesterday; 
will not eat. 
Nov. 30—11 a. m. —Chicken improving ; eats a little. 
Dec. 1—11 a. m. —Chicken appears to be all right; eats well. 
Dec. 2—11 a. m. —Chicken entirely recovered. 
Dec. 5—12:15 p. m. —Injected 25 minims of solution Helo- 
derma saliva into breast of chicken, same quantity into right leg, 
same quantity into left leg, making in all 75 minims. In a short 
time fowl had copious water discharge per anum , with a 
curious oscillatory movement of that opening. 
12:25.—Chicken lying down with its feathers much ruffled. 
Dec. 6—Chicken fouud dead. This fowl had been used for 
previous experiments, and was very thin and weak, and it is by 
no means certain whether the copious diarrhoea probably produced 
by the glycerine did not cause its death. 
Dec. 5.—Forced largest Heloderma to bite a chicken on the 
leg (from which feathers had been removed) several times. There 
was a copious flow of saliva and many larcerated wounds. 
Dec. 6.—Chicken seems perfectly well, no swelling or local 
manifestations whatever. 
Dec. 7.—Chicken perfectly well. 
Fearing that possibly the glycerine solution of venom (2drs. 
of saliva to 6drs. of glycerine) was too weak or had lost its 
strength through keeping, on Dec. 8 the following conclusive ex¬ 
periment was performed : 
12:15 p. m.— Forced open the jaws of the largest and most 
savage Heloderma and collected upon a piece of absorbent cotton 
from ten to fifteen drops of fresh saliva. An incision was made 
in the breast of a chicken and the cotton placed in it and al¬ 
lowed to remain. 
Dec. 10—The chicken appears perfectly well; no sign of in¬ 
disposition or local manifestations whatever. Wound appears to 
be healing kindly. 
Jan. 20, 1888—Wound in breast has been healed for some 
time, the cotton remains where it was placed and can be felt en¬ 
cysted under the skin and has produced no injury. 
