i6 
W. L. WILLIAMS. 
not so great as to clearly indicate glanders, a second or third 
trial may be necessary to determine if glanders exists. In 
some cases repeated injections of mallein increase, in other 
cases decrease the severity of glanders symptoms. Prof. A. 
Johne* of the Royal Veterinary school at Dresden tabulates 
the results of mallein tests upon forty-nine horses which had 
either been exposed to glanders or had shown symptoms which 
rendered them suspicious but not sufficiently definite, except in 
one case, to warrant a diagnosis of glanders. Of these twenty- 
five showed an increase of temperature of i° C. (i.8° F.) or more, 
of which twenty were destroyed and found upon post-mortem 
examination, glandered, the others upon re-testing were pro¬ 
nounced sound. Five animals somewhat suspicious before test¬ 
ing, but showing no elevation of temperature, were destroyed 
and found free from glanders. The other animals remained ap¬ 
parently sound. Professors Hutrya and Preiszf of Buda Pesth, 
Austria, review 486 tests with mallein upon horses exposed to 
or suspected of glanders, of which post-mortem examinations 
of 126 animals were made. Of this number twenty-two animals 
showed an elevation of temperature of less than 1.5 0 C. (2.7 F.), 
eight of which were found glandered, thirteen free ; fifteen horses 
showed a reaction of 1.5 0 to 2° C., all of which upon post-mortem 
were found glandered ; and eighty-nine animals reacted 2° C. or 
over, of which eighty-four were found glandered and five healthy. 
Of these five, one did not show the typical reaction described 
above, while in the other four the writers suspected serious errors 
either in the quality of mallein used or in the post-mortem ex¬ 
amination. H. Schindler, X chief veterinarian to the 7th Austrian 
hussars, after ineffectual attempts to stamp out glanders in his 
regiment by the ordinary means of destroying all those showing 
symptoms of the disease, used mallein upon twenty-six exposed 
horses, three of which reacted 2° or over, and after death, were 
found glandered. The three showing the next highest tempera- 
* Deutche Zeitschrift fur Thiermedecin, March, 1893. 
f Ibid, September, 1894. 
t GEsterrichischse Monatschrift fus Thierheilkunde, July, 1894. 
